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Current Studies

Cardiac Trials

Study – EX4758

  • eGFR ≥15 and < 60 mL/min/1.73 m2
  • Serum hs-CRP ≥2 mg/L at screening
  • Evidence of ASCVD by one or more of the following within the last 5 years from screening:
    • Coronary heart disease defined as at least one of the following:
    • Cerebrovascular disease defined as at least one of the following:
    • Symptomatic peripheral artery disease (PAD) defined as at least one of the following:

Type 1 Diabetes Trials:

Study – LPS14947

  • Participant must be 18 to 70 years of age.
  • Participants with T1DM.
  • Participants treated with multiple daily injections (MDI) using basal insulin analog once daily and rapid acting insulin analogs for at least one year.
  • HbA1c ≥7% (48 mmol/mol) and ≤ 10% (86 mmol/mol) at screening.

Study – NN4625

  • Male or female aged ≥ 18 years at the time of signing informed consent
  • Diagnosed with type 1 diabetes mellitus ≥ 1 year prior to the day of screening
  • Treated with multiple daily insulin injections (basal and bolus insulin analogue regimes)
  • HbA1c <10% at screening visit based on analysis from central laboratory.

Type 1 or 2 Diabetes Trials:

Study – CIP331

  • Individual is 2-80 years of age at time of consent
  • A clinical diagnosis of type 1 or type 2 diabetes as determined by investigator for:
    • at least the last 6 months for subjects 2-6 years of age
    • at least the last 12 months for subjects 7-80 years of age
  • Subject is on multiple daily injection therapy
  • Subject is currently using or is willing to use the Guardian Connect system during the study
  • Subject agrees to comply with the study protocol requirements

Study – CIP322

  • Individual is 2-75 years of age at time of enrollment.
  • Subject has a clinical diagnosis of type 1 or type 2 diabetes for a minimum of 6 months duration as determined via medical record/ source documentation by an individual qualified to make a medical diagnosis.
  • Subject is using insulin to treat their diabetes.
  • Subject agrees to comply with the study protocol requirements.
  • Subject is willing to perform SMBG approximately every 15 minutes /20 minutes during FST.
  • If subject is participating in YSI FST, subject has adequate venous access as assessed by investigator or appropriate staff.

Study – NN4635

  • Male or female, age above or equal to 18 years at the time of signing informed consent
  • Diagnosed with type 2 diabetes mellitus ≥ 180 days prior to the day of screening
  • HbA1c of 8.0-10.5%
  • BMI ≥ 25 kg/m2
  • Stable daily dose(s) for 90 days prior to the day of screening of any of the following treatment regimens:
    • No more than 3 of the following oral anti-diabetic drugs and at least 1 marked with a *:
      • * Metformin
      • * Sulfonylureas
      • * SGLT2 inhibitors
      • *DPP-4 inhibitors
 
Endocrine Research Solutions, Inc.
1475 Holcomb Bridge Road, Suite 129, Roswell, GA 30076
Ph: 678.878.4750 Fx: 678.878.4751